Cerebro
Table of Contents
Archetype pages are updated after each Tier List is made. If a page isn’t up-to-date, it means there was nothing worth mentioning in the last report, either because there was no data about the archetype or it did poorly.
How to Play
No matter which number you pick for the power of your cards in a Cerebro deck, your overall game plan will not change too much. Most of the time, Cerebro and Mystique will take two spots in the deck while not contributing to the overall total (except in Cerebro 3 with Bast and Valkyrie); therefore, as long as you don’t fear an opposing Enchantress, they should be played on the same location. This way you have all four spots available to contest the other two locations, and all four are usually needed for the win. This positioning can be extremely important, especially in low-power Cerebro decks.
Once you know where you want to invest most of your power, the second critical part of a Cerebro deck is abusing your cards’ abilities. Indeed, finding powerful abilities is the key to making a good Cerebro deck, especially when you have to work with cards with only two or three power.
Let’s use Cerebro 3 as an example. Your cards are able to get as high as seven power (if everything goes according to plan) and create two 28-power locations; however, if you only win games in that precise scenario, your Win Rate will be quite low over a large sample size.
In that Cerebro 3 deck, Mobius M. Mobius, Valkyrie, and Scarlet Witch are very good cards to disrupt your opponent, and you pack some flexibility with Wasp and Jeff the Baby Land Shark. You also have big power potential with Iron Man. This archetype is also very flexible when it comes to disruptive cards it wants to include. Tools like Armor, Cosmo, Shang-Chi, and Killmonger are simple to include if you feel they would help against your popular opponents.
It is through these kinds of inclusions that make the popular Cerebro decks much more than an assembly of cards with the same power. They have the ability to counter other archetypes and take the fight to a level other than the basic “who can develop the most points by the end of Turn 6”. When playing a Cerebro deck, then, it’s important to remember your points ceiling is not the best (hence why Cerebro isn’t highly regarded in the community). Still, you haven’t included these precise cards for their power, so finding value in their abilities is the difference between a bad Cerebro player and one racking up cubes on their way to Infinite.
Current Cerebro Builds
Cerebro 3
Created by 
den
den, updated 4 days ago
1x Collection Level 222-474 (Pool 2)
5x Collection Level 486+ (Pool 3)
2x Series 4 Rare – Collection Level 486+ (Pool 4)
2x Series 5 Ultra Rare – Collection Level 486+ (Pool 5)
2x Starter Card
2.8
Cost
2.1
Power
Cerebro 2
Created by den
den, updated 21 days ago
1x Collection Level 1-14
2x Collection Level 18-214 (Pool 1)
1x Collection Level 222-474 (Pool 2)
5x Collection Level 486+ (Pool 3)
2x Series 5 Ultra Rare – Collection Level 486+ (Pool 5)
1x Recruit Season
2.3
Cost
1.8
Power
Cerebro 5
Created by den
den, updated 2 months ago
2x Collection Level 18-214 (Pool 1)
6x Collection Level 486+ (Pool 3)
1x Series 4 Rare – Collection Level 486+ (Pool 4)
2x Series 5 Ultra Rare – Collection Level 486+ (Pool 5)
1x Recruit Season
2.8
Cost
3.9
Power
Guides
Current Power Level in the Meta
The surprise performer of the week, Cerebro 3 had an absolutely nuts performance or a really good week depending which source you look at. In the biggest sample size, the deck managed to win 54% of its games while racking up and average of 0.4 cubes.
In particular, I can’t stress enough how good Quake and U.S. Agent are right now. Quake is great because a more confusing environment and more impactful locations give you something to rely on and plan around. U.S. Agent is great because Leech, Jubilee, and Blink are all high cost cards, which means you can dismantle their lane with a 2-Cost. On average, U.S. Agent is a [2/7] since its buff, and it’s a top tier card in the entire game if you can reliably make it a [2/11].
Conquest Performance
Cerebro 5
Created by den
den, updated 8 days ago
2x Collection Level 18-214 (Pool 1)
7x Collection Level 486+ (Pool 3)
2x Series 5 Ultra Rare – Collection Level 486+ (Pool 5)
1x Starter Card
3.3
Cost
4.3
Power
Nocturne is a nice addition to Cerebro 5, but I believe Enchantress is the real star of the show in this meta after the Ongoing synergy gained lots of momentum.
The deck only averaged a 52% Win Rate, which is the lowest a deck needs to be considered in this report, so I wouldn’t say Cerebro 5 is doing particularly well right now. Still, those satellite decks we don’t always see on these rankings can tip us onto what could be good in the meta right now. Their presence here means they are doing something right at the moment.
Archetype Evolution Over Time
- Cerebro 3 did great early in the season and posted the highest Cube Rate in the game (although it was over a limited sample size of games).
- Cerebro 2 is doing fairly well currently after managing to gain some popularity. The metrics are on the lower end compared to the other decks in our Tier List, but just being in there is often a good sign for Cerebro.
- Cerebro 5 got a decent boost of momentum with the OTA, even if it didn’t make it as more than a fun archetype to explore. Cerebro 2 and 3 didn’t do anything worth noting this week.
- Cerebro 3 was a Silent Performer this week and represented the disruptive synergies quite well. With a bigger sample size, the deck could have been considered a low Tier 2 build.
- No Cerebro deck has been popular enough in the new season thus far, so it’s impossible to know their worth apart from the fact that they are not seeing much play.